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Vet Rec 1988 Nov 19;123(21):533-536
Ontario Veterinary College, University of Guelph, Canada.
A three-week old male Charolais calf which had a history of progressive hair
loss and clinical signs, including crusts and brown patches similar to those
in folic acid deficiency syndrome in man, was subjected to folic acid therapy.
Daily oral administration of folic acid (1 mg/kg/day) resulted in the gradual
disappearance of the crusts and patches within two weeks and a steady growth
of hair and recovery to a normal state within two months. Folic acid, which
is required for cellular turnover in a variety of tissues and organs including
the hair follicle, may serve as an effective therapeutic agent in some types
of alopecia triggered by a deficiency of either folic acid or the co-enzymes
involved in the synthetic pathway of DNA.
PMID: 3206804, UI: 89085562
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